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Chromosome 14 - Immunoglobulins: Building Our Immune

EXPLORE THE RI ADVENT CALENDAR: rigb.org.uk/advent Do you trust your sense of smell? We usually consider our senses to be relatively reliable and would expect a certain ...

EXPLORE THE RI ADVENT CALENDAR: rigb.org.uk/advent Do you trust your sense of smell? We usually consider our ...

EXPLORE THE RI ADVENT CALENDAR: rigb.org.uk/advent Do you trust your ...

Chromosome 14 - Immunoglobulins: Building Our Immune System

EXPLORE THE RI ADVENT CALENDAR: rigb.org.uk/advent In order to defend our bodies, our immune system has to be able to recognise and destroy an incredibly vast number of pathogens. It's surprising, then, that it manages to do so with a relatively small set of genes, called immunoglobulins -- one of which is found on chromosome 14. Aoife McLysaght from Trinity College Dublin explains how recombination of this gene allows us to produce a ...

EXPLORE THE RI ADVENT CALENDAR: rigb.org.uk/advent In order to defend our bodies, our immune system has to be able to recognise and destroy an incredibly vast number of pathogens. It's surprising, then, that it manages to do ...

EXPLORE THE RI ADVENT CALENDAR: rigb.org.uk/advent In order to defend our bodies, our immune system has to be able to recognise and ...

Chromosome 15 - Eye Colour

EXPLORE THE RI ADVENT CALENDAR: rigb.org.uk/advent The human eye is a remarkable feat of engineering, but from the outside the main thing we notice is the colour. Eye colour is partly dictated by a gene on chromosome 15 called OCA2, which gives instructions for the production of a pigment called melanin. Dr Tim Cockerill explains how different amounts of melanin lead to different eye colours, and how the production of blue eyes can ...

EXPLORE THE RI ADVENT CALENDAR: rigb.org.uk/advent The human eye is a remarkable feat of engineering, but from the outside the main thing we notice is the colour. Eye colour is partly dictated by a gene on chromosome 15 ...

EXPLORE THE RI ADVENT CALENDAR: rigb.org.uk/advent The human eye is a remarkable feat of engineering, but from the outside the main thing ...

Chromosome 16 - Genetically Ginger

Ginger hair is often singled out, but whilst the visual difference is quite striking, when you look at the genetic code it's all but indistinguishable. The gene that can give rise to ginger hair is called melanochortin1 receptor (MC1R) and is found on chromosome 16. As the Ri's red-headed CHRISTMAS LECTURES researcher Andrew Beale explains, this gene controls the kind of pigment that will be produced in a person's hair. The difference between brown hair ...

Ginger hair is often singled out, but whilst the visual difference is quite striking, when you look at the genetic code it's all but indistinguishable. The gene that can give rise to ginger hair is called melanochortin1 receptor (MC1R) ...

Ginger hair is often singled out, but whilst the visual difference is quite striking, when you look at the genetic code it's all but indistinguishable. ...

Chromosome 17 - A Strange Sense Of Smell

EXPLORE THE RI ADVENT CALENDAR: rigb.org.uk/advent Do you trust your sense of smell? We usually consider our senses to be relatively reliable and would expect a certain substance to smell the same to different people. Thanks to small genetic variations in a gene called OR7D4 on chromosome 17, however, something which smells like flowers to one person might smell like stale sweat or urine to someone else. As Aoife McLysaght from Trinity ...

EXPLORE THE RI ADVENT CALENDAR: rigb.org.uk/advent Do you trust your sense of smell? We usually consider our senses to be relatively reliable and would expect a certain substance to smell the same to different people. Thanks to ...

EXPLORE THE RI ADVENT CALENDAR: rigb.org.uk/advent Do you trust your sense of smell? We usually consider our senses to be relatively reliable ...

Chromosome 18 - Junk Dna, Or Is It?

EXPLORE THE RI ADVENT CALENDAR: rigb.org.uk/advent Of all our chromosomes, chromosome 18 is the least dense in terms of genes, with barely any of its rather paltry 76 million base pairs encoding actual genes. As with the rest of the human genome, a large portion of it is considered junk DNA , so called because it doesn't appear to have any particular function. There might just be a reason, however, that these seemingly pointless sequences ...

EXPLORE THE RI ADVENT CALENDAR: rigb.org.uk/advent Of all our chromosomes, chromosome 18 is the least dense in terms of genes, with barely any of its rather paltry 76 million base pairs encoding actual genes. As with the rest of ...

EXPLORE THE RI ADVENT CALENDAR: rigb.org.uk/advent Of all our chromosomes, chromosome 18 is the least dense in terms of genes, with barely any ...

Chromosome 19 - Keeping Things Moving

EXPLORE THE RI ADVENT CALENDAR: rigb.org.uk/advent We all need a bit of cholesterol as it's used in our cell membranes, but too much of it can put us at risk of cardiovascular disease. One of the most dangerous types of cholesterol is low-density lipoproteins (LDLs). Usually LDLs are removed from our bloodstream by LDL receptors -- proteins which are coded for by a gene on chromosome 19. Using the London underground as an ...

EXPLORE THE RI ADVENT CALENDAR: rigb.org.uk/advent We all need a bit of cholesterol as it's used in our cell membranes, but too much of it can put us at risk of cardiovascular disease. One of the most ...

EXPLORE THE RI ADVENT CALENDAR: rigb.org.uk/advent We all need a bit of cholesterol as it's used in our cell membranes, but too ...

Chromosome 20 - Male Pattern Baldness

EXPLORE THE RI ADVENT CALENDAR: rigb.org.uk/advent Gentlemen, are you follicly challenged, or heading that way? It has always been assumed that the cause of male baldness lies with the X chromosome and is therefore an inherited trait passed down the maternal line. But what if yours is the only bald head shining out in family photos? Eggheads (in more ways than one) Prof Andrea Sella and Prof Mark Miodownik from University College ...

EXPLORE THE RI ADVENT CALENDAR: rigb.org.uk/advent Gentlemen, are you follicly challenged, or heading that way? It has always been assumed that the cause of male baldness lies with the X chromosome and is therefore an inherited trait ...

EXPLORE THE RI ADVENT CALENDAR: rigb.org.uk/advent Gentlemen, are you follicly challenged, or heading that way? It has always been assumed that the ...

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